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Sarcoma indiferenciado primário no sistema nervoso central / Primary undifferentiated sarcoma of the central nervous system
Machota Junior, Milton Marcio; Gentili, Arthur Cornelian; Marques, Fabricio Machado; Maciel, Paulo Roberto; Ogata, Silvio Atsushi; Bleggi-Torres, Luiz Fernando.
  • Machota Junior, Milton Marcio; s.af
  • Gentili, Arthur Cornelian; s.af
  • Marques, Fabricio Machado; s.af
  • Maciel, Paulo Roberto; s.af
  • Ogata, Silvio Atsushi; s.af
  • Bleggi-Torres, Luiz Fernando; s.af
J. bras. patol. med. lab ; 48(2): 135-138, abr. 2012. ilus
Article Dans Portugais | LILACS | ID: lil-623373
RESUMO

INTRODUÇÃO:

O sarcoma de sistema nervoso central (SNC) é uma neoplasia rara, com incidência de 0,1% a 4,3% dos tumores intracranianos. São tumores agressivos com prognóstico reservado e a maioria é tratada com ressecção radical. RELATO Homem, 29 anos, com episódios de crises convulsivas e diagnóstico de hemorragia intraparenquimatosa. Durante a cirurgia, foi identificada lesão bem delimitada. A histologia demonstrou neoplasia fusocelular com atipias e numerosas mitoses. Os únicos marcadores imuno-histoquímicos positivos foram vimentina e S-100. O diagnóstico foi de sarcoma indiferenciado de alto grau.

CONCLUSÃO:

No diagnóstico diferencial de sarcomas de SNC, devem-se excluir lesões metastáticas e gliossarcoma.
ABSTRACT

INTRODUCTION:

The central nervous system (CNS) sarcoma is a rare neoplasm with an incidence of 0.1% to 4.3% in intracranial tumors. They are aggressive with poor prognosis, and mostly treated with radical resection. REPORT 29 year-old male patient with episodes of seizures and diagnosed with intraparenchymal hemorrhage. During the surgery a well-defined lesion was identified. Histology showed a spindle cell neoplasm with atypia and numerous mitoses. The immunohistochemical markers were positive only for vimentin and S-100. The diagnosis was high-grade undifferentiated sarcoma.

CONCLUSION:

Metastatic lesions and gliosarcoma should be excluded in the differential diagnosis of CNS sarcomas.
Sujets)


Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Sarcomes / Système nerveux central / Diagnostic différentiel Type d'étude: Etude diagnostique / Étude pronostique Limites du sujet: Adulte / Humains / Mâle langue: Portugais Texte intégral: J. bras. patol. med. lab Thème du journal: Pathologie Année: 2012 Type: Article

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Sarcomes / Système nerveux central / Diagnostic différentiel Type d'étude: Etude diagnostique / Étude pronostique Limites du sujet: Adulte / Humains / Mâle langue: Portugais Texte intégral: J. bras. patol. med. lab Thème du journal: Pathologie Année: 2012 Type: Article