Ethnobotanical, pharmacognostical, pharmacological and phytochemical studies on Smilax domingensis in Guatemala
Rev. bras. farmacogn
;
22(2): 239-248, Mar.-Apr. 2012. ilus, graf
Article
Dans Anglais
| LILACS
| ID: lil-624661
ABSTRACT
Smilax domingensis Willd., Smilacaceae, known as zarzaparrilla, is a climbing shrub from Tropical America. The rhizome is popularly used in medicine as anti-inflammatory, antiseptic, and tonic. Since 1983 studies are being conducted in Guatemala for validation of the ethnobotanical uses, particularly in vitro demonstration of antimicrobial activity, using wild material, with high variability and some taxonomic problems. This article reports the taxonomic determination, cultivation of drug material, evaluation of use by in vitro and in vivo pharmacological assays, and phytochemical characterization. Extracts from cultivated material was evaluated by antimicrobial, anti-inflammatory, analgesic and immunomodulatory models, confirming the antimicrobial and immunomodulatory activities. Phytochemistry was done in the crude drug and extracts. Quality control parameters are described (micrographic drawings and phytochemical characteristics). Evidence is presented that cultivated rhizome has antimicrobial and immunomodulatory activities, validating the popular use and helping the industrial development of phytopharmaceutical products.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Type d'étude:
Étude pronostique
Pays comme sujet:
Amérique centrale
/
Guatémala
langue:
Anglais
Texte intégral:
Rev. bras. farmacogn
Thème du journal:
Pharmacie
Année:
2012
Type:
Article
Pays d'affiliation:
Argentine
/
Guatemala
Institution/Pays d'affiliation:
Universidad Nacional de Rosario/AR
/
Universidad de San Carlos/GT
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