Comparative analysis of the intracerebral mouse protection test and serological method for potency assays of pertussis component in DTP vaccine
Braz. j. microbiol
;
43(2): 429-431, Apr.-June 2012. graf, tab
Article
Dans Anglais
| LILACS
| ID: lil-644455
ABSTRACT
The aim of this study was to compare the PSPT standardized in-house as an alternative to MPT for potency assays of pertussis component. Statistical analyses have showed similar pertussis potency values when PSPT was compared to MPT. Significant correlation between the potency results obtained by in vivo and in vitro assays was also been observed. Results by PSPT have demonstrated reproducibility and accuracy for potency pertussis control and this approach has been considered promising for use at least during the steps of production.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Bordetella pertussis
/
Coqueluche
/
Technique EMIT
/
Techniques et procédures diagnostiques
Type d'étude:
Etude diagnostique
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Braz. j. microbiol
Thème du journal:
Microbiologie
Année:
2012
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Fundação Instituto Oswaldo Cruz/BR
/
Instituto Butantan/BR
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