Protective effects of Tualang honey on bone structure in experimental postmenopausal rats
Clinics
;
67(7): 779-784, July 2012. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-645451
ABSTRACT
OBJECTIVE:
The objective of this study was to evaluate the effects of Tualang honey on trabecular structure and compare these effects with those of calcium supplementation in ovariectomized rats.METHODS:
Forty female, Sprague-Dawley rats were randomly divided into five groups (n =8) four controls and one test arm. The control arm comprised a baseline control, sham-operated control, ovariectomized control, and ovariectomized calcium-treated rats (receiving 1% calcium in drinking water ad libitum). The test arm was composed of ovariectomized, Tualang honey-treated rats (received 0.2 g/kg body weight of Tualang honey). Both the sham-operated control and ovariectomized control groups received vehicle treatment (deionized water), and the baseline control group was sacrificed without treatment.RESULTS:
All rats were orally gavaged daily for six weeks after day one post-surgery. The bone structural analysis of rats in the test arm group showed a significant increase in the bone volume per tissue volume (BV/TV), trabecular thickness (Tb.Th) and trabecular number (Tb.N) and a significant decrease in inter-trabecular space (Tb.Sp) compared with the ovariectomized control group. The trabecular thickness (Tb.Th) in the test arm group was significantly higher compared with the ovariectomized-calcium treated group, and the inter-trabecular space (Tb.Sp) in the test arm group was significantly narrower compared with the ovariectomized-calcium treated group.CONCLUSION:
In conclusion, ovariectomized rats that received Tualang honey showed more improvements in trabecular bone structure than the rats that received calcium.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Calcium alimentaire
/
Densité osseuse
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Compléments alimentaires
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Apithérapie
/
Miel
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Clinics
Thème du journal:
Médicament
Année:
2012
Type:
Article
/
descriptif de projet
Pays d'affiliation:
Malaisie
Institution/Pays d'affiliation:
Universiti Kebangsaan Malaysia/MY
/
Universiti Putra Malaysia/MY
/
Universiti Sains Malaysia/MY
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