Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
Acta cir. bras
;
28(2): 94-101, Feb. 2013. ilus, graf, tab
Article
Dans Anglais
| LILACS
| ID: lil-662355
ABSTRACT
PURPOSE:
To compare the degree of neural regeneration in rats upon interposition of autologous nerve graft, autogenous vein, glycerol-preserved autogenous vein, and glycerol-preserved allogeneic vein using qualitative and quantitative histological analyses as well as functional assessments.METHODS:
Peroneal nerves were reconstructed differently in four groups of animals. Functional assessments were performed pre- and postoperatively for a period of six weeks. After six weeks, the animals were sacrificed and histological evaluations were performed.RESULTS:
Histological patterns of autogenous veins without preservation showed pronounced neoangiogenesis and extensive axonal rarefaction, as confirmed by axonal counting and functional assessments. Glycerol-preserved veins had results similar to the control.CONCLUSIONS:
Glycerol-preserved autogenous or allogeneic veins showed similar results to autograft results. The autogenous vein (without preservation in glycerol) presented histological and functional outcomes statistically lower than other groups.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Nerf fibulaire commun
/
Conservation de tissu
/
Glycérol
/
Veines jugulaires
/
Régénération nerveuse
Type d'étude:
Recherche qualitative
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Acta cir. bras
Thème du journal:
Chirurgie générale
/
Procedimentos Cir£rgicos Operat¢rios
Année:
2013
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
USP/BR
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