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Outbreak of carbapenem-resistant Klebsiella pneumoniae: two-year epidemiologic follow-up in a tertiary hospital
Pereira, Graziella Hanna; Garcia, Doroti O; Mostardeiro, Marcelo; Fanti, Karina SVN; Levin, Anna S.
  • Pereira, Graziella Hanna; Hospital Brigadeiro. Departamento de Controle de Infecção. São Paulo. BR
  • Garcia, Doroti O; Hospital Brigadeiro. Departamento de Controle de Infecção. São Paulo. BR
  • Mostardeiro, Marcelo; Hospital Brigadeiro. Departamento de Controle de Infecção. São Paulo. BR
  • Fanti, Karina SVN; Hospital Brigadeiro. Departamento de Controle de Infecção. São Paulo. BR
  • Levin, Anna S; Hospital Brigadeiro. Departamento de Controle de Infecção. São Paulo. BR
Mem. Inst. Oswaldo Cruz ; 108(1): 113-115, Feb. 2013. graf
Article Dans Anglais | LILACS | ID: lil-666054
ABSTRACT
This study describes a carbapenem-resistant Klebsiella pneumoniae (CRKP) outbreak that occurred from October 2008-December 2010. Polymerase chain reaction assays were performed to detect the blaKPC gene and molecular typing was performed using pulsed-field gel electrophoresis (PFGE). There were 33 CRKP infections; PFGE revealed five genotypes genotype A in five (15%), B in 18 (55%), C in eight (24%) and two unique profiles. Genotype B was disseminated in all hospital units and belonged to the same clone identified in 11 different hospitals in the state of São Paulo. Sixteen (48%) patients died. Seven isolates (21%) were resistant to polymyxin B and 45% were resistant to tigecycline and amikacin.
Sujets)


Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Infections à Klebsiella / Carbapénèmes / Infection croisée / Épidémies de maladies / Résistance aux bêta-lactamines / Klebsiella pneumoniae / Antibactériens Limites du sujet: Adolescent / Adulte / Adulte très âgé / Aged80 / Enfant / Enfant d'âge préscolaire / Femelle / Humains / Mâle langue: Anglais Texte intégral: Mem. Inst. Oswaldo Cruz Thème du journal: Médecine tropicale / Parasitologie Année: 2013 Type: Article / descriptif de projet Pays d'affiliation: Brésil Institution/Pays d'affiliation: Hospital Brigadeiro/BR

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Infections à Klebsiella / Carbapénèmes / Infection croisée / Épidémies de maladies / Résistance aux bêta-lactamines / Klebsiella pneumoniae / Antibactériens Limites du sujet: Adolescent / Adulte / Adulte très âgé / Aged80 / Enfant / Enfant d'âge préscolaire / Femelle / Humains / Mâle langue: Anglais Texte intégral: Mem. Inst. Oswaldo Cruz Thème du journal: Médecine tropicale / Parasitologie Année: 2013 Type: Article / descriptif de projet Pays d'affiliation: Brésil Institution/Pays d'affiliation: Hospital Brigadeiro/BR