Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes
Biol. Res
;
46(1): 39-45, 2013. ilus
Article
Dans Anglais
| LILACS
| ID: lil-676819
ABSTRACT
Carotenoids are efficient antioxidants that are of great importance for human health. Lutein and zeaxanthin are carotinoids present in high concentrations in the human retina which are involved in the photoprotection of the human eye. Lutein may also protect the skin from ultraviolet (UV)-induced damage. The present study investigated the protective effect of lutein extracted from yellow silk cocoons of Bombyx mori on human keratinocytes against UVB irradiation. A human keratinocyte cell line and primary human keratinocytes were used to investigate the UVB protection effects of silk lutein and plant lutein. Silk lutein showed no cytotoxicity to keratinocytes. Treatment with silk lutein prior to UVB irradiation enhanced cell viability and cell proliferation, and reduced cell apoptosis. The protective effects of silk lutein may be superior to those of plant lutein. Silk lutein may have a benefit for protection of keratinocytes against UVB-irradiation.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Radioprotecteurs
/
Rayons ultraviolets
/
Lutéine
/
Kératinocytes
/
Soie
Limites du sujet:
Animaux
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Biol. Res
Thème du journal:
Biologie
Année:
2013
Type:
Article
Pays d'affiliation:
Thaïlande
Institution/Pays d'affiliation:
Naresuan University/TH
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