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What is the rea impairment on esophageal motilty in patients with gastroesophhageal reflux disease?
Arquivos de Gastroenterologia; FALCAO, Angela; NASI, Ary; BRANDAO, Jeovana; SALLUM, Rubens; CECCONELLO, Ivan.
Affiliation
  • FALCAO, Angela; Esophageal Surgery Service. Esophageal Surgery Service.
  • NASI, Ary; Esophageal Surgery Service. Esophageal Surgery Service.
  • BRANDAO, Jeovana; Esophageal Surgery Service. Esophageal Surgery Service.
  • SALLUM, Rubens; Esophageal Surgery Service. Esophageal Surgery Service.
  • CECCONELLO, Ivan; Esophageal Surgery Service. Esophageal Surgery Service.
Arq. gastroenterol ; Arq. gastroenterol;50(2): 111-116, abr. 2013. tab, graf
Article de En | LILACS | ID: lil-679157
Bibliothèque responsable: BR1.1
ABSTRACT
Context Impairment of esophageal motility is a common finding in patients with gastroesophageal reflux disease (GERD) as reduced lower esophageal sphincter (LES) basal pressure. A very low LES pressure might facilitate the occurrence of more gastroesophageal reflux whereas abnormal esophageal peristalsis may contribute to impaired esophageal clearance after reflux. Objective Evaluate the esophageal motor function of the lower esophageal sphincter and esophageal body in the various forms of gastroesophageal reflux disease. Methods The manometrics records of 268 patients, who had evaluation of the esophageal motility as part of the diagnostic gastroesophageal reflux disease were split into four groups, as follows 33 patients who had no esophagitis; 92 patients who had erosive esophagitis; 101 patients who had short Barrett's esophagus and 42 patients who had long Barrett's esophagus. Results The group who had long Barrett's esophagus showed smaller mean LES pressure and higher percentage of marked LES hypotonia; in the distal segment of the esophageal body the this group showed higher percentage of marked hypocontractility of the distal segment (<30 mm Hg); this same group showed higher percentage of esophageal motility disorders. Conclusions The most intense esophageal motility disorders and lower pressure of lower esophageal sphincter were noted in the group with long Barrett's esophagus. Those with reflux esophagitis and short Barrett's esophagus had esophageal motility impairment, intermediate among patients with esophagitis and long Barrett's esophagus. Patients with typical symptoms of gastroesophageal reflux but without esophagitis by endoscopy study showed no impairment of esophageal motility. .
RESUMO
Contexto Alteração no peristaltismo esofágico assim como diminuição do tônus basal do esfíncter inferior do esôfago são um achado comum em pacientes com doença do refluxo gastroesofágico. A presença de hipotonia acentuada do esfíncter inferior do esôfago pode facilitar a ocorrência de refluxo gastroesofágico mais intenso e a presença de alteração no peristaltismo esofágico pode contribuir para uma deficiente depuração esofágica. Objetivo Avaliar a função motora do esfíncter inferior do esôfago e do corpo esofágico nas várias formas da doença do refluxo gastroesofágico. Métodos Avaliaram-se os prontuários de 268 pacientes, que realizaram manometria esofágica como parte da investigação diagnóstica da doença do refluxo gastroesofágico. Os pacientes foram distribuidos em quatro grupos 33 pacientes que não tinham esofagite, 92 pacientes que tinham esofagite erosiva; 101 pacientes que tinham esôfago de Barrett curto e 42 pacientes que tinham esôfago de Barrett longo (grupo EBL). Resultados O grupo dos que tinham EBL, apresentou menor média de pressão do esfíncter inferior do esôfago e maior percentual de hipotonia acentuada do esfíncter inferior do esôfago; no segmento distal do corpo do esôfago, este grupo apresentou maior percentual de hipocontratilidade acentuada (< 30 mm Hg). O grupo dos que tinham EBL apresentou maior porcentagem de distúrbios da motilidade esofágica. Conclusões As alterações mais intensas na motilidade esofágica e no esfíncter inferior do esôfago foram observadas no grupo com EBL. Aqueles com esofagite de refluxo e esôfago de Barrett curto ...
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Texte intégral: 1 Indice: LILACS Sujet Principal: Oesophage de Barrett / Dyskinésies oesophagiennes / Reflux gastro-oesophagien / Sphincter inférieur de l'oesophage / Oesophagite Type d'étude: Diagnostic_studies / Observational_studies / Risk_factors_studies Limites du sujet: Adult / Female / Humans / Male langue: En Texte intégral: Arq. gastroenterol Thème du journal: GASTROENTEROLOGIA Année: 2013 Type: Article

Texte intégral: 1 Indice: LILACS Sujet Principal: Oesophage de Barrett / Dyskinésies oesophagiennes / Reflux gastro-oesophagien / Sphincter inférieur de l'oesophage / Oesophagite Type d'étude: Diagnostic_studies / Observational_studies / Risk_factors_studies Limites du sujet: Adult / Female / Humans / Male langue: En Texte intégral: Arq. gastroenterol Thème du journal: GASTROENTEROLOGIA Année: 2013 Type: Article