The effect of carbon dioxide therapy on composite graft survival
Acta cir. bras
;
28(8): 589-593, Aug. 2013. ilus, graf
Article
Dans Anglais
| LILACS
| ID: lil-680613
ABSTRACT
PURPOSE:
To investigate the effect of carboxytherapy in auricular composite grafts in rabbits.METHODS:
An experimental study was conducted using 20 rabbits randomly assigned to a treatment group of carboxytherapy or a control group of saline solution. In each ear, a circular graft with 1.5 cm or 2 cm of diameter was amputated and reattached. Animals underwent carbon dioxide or saline injection four times during the experiment. We analyzed clinical evolution of the animals, grafts survival, histopathology features and histomorphometry of collagen.RESULTS:
The treated group had a significantly lower weight gain (p=0.038). Histopathology was not significantly different between groups. There was an increase in amount of collagen in 2 cm grafts submitted to carbon dioxide therapy (p=0.003). Carboxytherapy didn't influence graft survival rate for 1.5 cm grafts or 2 cm grafts (p=0.567 and p=0.777, respectively).CONCLUSIONS:
Carbon dioxide therapy increased the amount of collagen in 2 cm grafts. CO2 was not significantly different from saline infusion on composite grafts survival, but this study suggests that there is a mechanical effect caused by distension which favored graft survival.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Dioxyde de carbone
/
Auricule de l'oreille
/
Survie du greffon
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Acta cir. bras
Thème du journal:
Chirurgie générale
/
Procedimentos Cir£rgicos Operat¢rios
Année:
2013
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
UnB/BR
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