Characteristics of hemolytic activity induced by skin secretions of the frog Kaloula pulchra hainana
J. venom. anim. toxins incl. trop. dis
;
19: 9-9, maio 2013. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-686619
ABSTRACT
Background:
Previous works had shown that scorpion venom induced neurotransmitter elevation and an inflammatory response associated with various anatomo-pathological modifications. The most dangerous scorpions species in Algeria responsible for these effects are Androctonus australis hector (Aah) and Androctonus amoreuxi (Aam).Results:
Comparison of the physiopathological effects induced by the two venoms showed differences in the kinetic of cytokine release and in lung injury. The lung edema was only observed in response to Aah venom and it was correlated with cell infiltration. In order to better understand the involved mechanism in inflammatory response, we used two antagonists, atropine (non-selective muscarinic antagonist) and propranolol (ß adrenergic antagonist), which lead to a decrease of cell infiltration but has no effect on edema forming.Conclusion:
These results suggest another pathway in the development of lung injury following envenomation with Aam or Aah venom.(AU)
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Peau
/
Bufo rana
/
Hémolyse
/
Amphibiens
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
J. venom. anim. toxins incl. trop. dis
Thème du journal:
Toxicologie
Année:
2013
Type:
Article
Pays d'affiliation:
Chine
Institution/Pays d'affiliation:
Hainan University/CN
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS