Animal models of neurodegenerative diseases
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
35(supl.2): S82-S91, 2013. graf
Article
Dans Anglais
| LILACS
| ID: lil-691406
ABSTRACT
The prevalence of neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD), increases with age, and the number of affected patients is expected to increase worldwide in the next decades. Accurately understanding the etiopathogenic mechanisms of these diseases is a crucial step for developing disease-modifying drugs able to preclude their emergence or at least slow their progression. Animal models contribute to increase the knowledge on the pathophysiology of neurodegenerative diseases. These models reproduce different aspects of a given disease, as well as the histopathological lesions and its main symptoms. The purpose of this review is to present the main animal models for AD, PD, and Huntington's disease.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Maladie de Parkinson
/
Maladie de Huntington
/
Modèles animaux de maladie humaine
/
Maladie d'Alzheimer
Type d'étude:
Facteurs de risque
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Thème du journal:
Psychiatrie
Année:
2013
Type:
Article
/
descriptif de projet
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Federal de Minas Gerais/BR
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