Puerperal brain cryptococcoma in an HIV-negative woman successfully treated with fluconazole: a case report
Rev. Soc. Bras. Med. Trop
;
47(2): 254-256, Mar-Apr/2014. graf
Article
Dans Anglais
| LILACS
| ID: lil-710359
ABSTRACT
Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV-negative woman diagnosed with a large cryptococcoma in the immediate postpartum period. The lesion was not resected, and due to amphotericin B intolerance, she received an extended course of fluconazole monotherapy. There was no disease recurrence during the 4 years of follow-up. The abrupt onset of her symptoms following delivery suggests that she developed a postpartum immune reconstitution syndrome. This case also demonstrates that in specific situations fluconazole monotherapy can be attempted in immunocompetent patients with cryptococcoma.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Infection puerpérale
/
Fluconazole
/
Méningite cryptococcique
/
Antifongiques
Type d'étude:
Etude diagnostique
Limites du sujet:
Adulte
/
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2014
Type:
Article
/
descriptif de projet
Pays d'affiliation:
États-Unis d'Amérique
Institution/Pays d'affiliation:
Yale School of Public Health/US
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