Antiperoxidative properties of oil mixes of high ratio Omega-9:Omega-6 and low ratio Omega-6:Omega-3 after molar extraction in rats
Acta cir. bras
;
29(6): 371-375, 06/2014. tab, graf
Article
Dans Anglais
| LILACS
| ID: lil-711590
ABSTRACT
PURPOSE:
To evaluate the antioxidant and antiperoxidative effects of oil mixes of high ratio Omega-9Omega-6 and low ratio Omega-6Omega-3 in the third day after tooth extraction in rats.METHODS:
Thirty-two male Wistar rats (270-310g) were randomly distributed in two groups Control (n=24) and Test (n=8). Control group was divided into three subgroups (n=8) G1 Sham-Saline; G2 Saline; G3 Isolipid. G1 and G2 animals received NaCl 0.9% while G3 rats were treated with an isolipid mixture (alpha-linolenic acid - ALA) containing -6/-3 oils (81 ratio) and-9/-6 (0.41 ratio). Test group animals (G4) received oily mixtures (alpha-linolenic acid - ALA, docosahexaenoic acid - DHA, eicosapentaenoic acid - EPA) of -6/-3 (1.41 ratio) and -9/-6 (3.41 ratio). Saline and oils were administered by gavage during four days before and three days after first mandibular molar extraction. Following, samples (arterial blood and alveolar mucosa) were collected for glutathione (GSH) and thiobarbituric acid reactive substances (TBARS) assays.RESULTS:
Oil mixes induced a significant decrease in GSH and TBARS tissue and plasma concentrations in the third day post-surgery.CONCLUSION:
Gavage administration of oil mixes of high ratio Omega-9Omega-6 and low ratio Omega-6Omega-3 after molar extraction in rats induces a significant decrease in lipid peroxidation. .
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Extraction dentaire
/
Peroxydation lipidique
/
Stress oxydatif
/
Acides gras
Type d'étude:
Études d'évaluation
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Acta cir. bras
Thème du journal:
Chirurgie générale
/
Procedimentos Cir£rgicos Operat¢rios
Année:
2014
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Federal University of Ceara/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS