Prevalence of high-risk human papillomavirus by cobas 4800 HPV test in urban Peru
Braz. j. infect. dis
; Braz. j. infect. dis;18(5): 469-472, Sep-Oct/2014. tab
Article
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| ID: lil-723088
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BR1.1
ABSTRACT
Background:
Molecular tests allow the detection of high-risk human papillomavirus in cervical samples, playing an important role in the prevention of cervical cancer.Objectives:
We performed a study to determine the prevalence of HPV 16, HPV 18 and other high-risk human papillomavirus (pool 12 genotypes) in Peruvian females from diverse urban areas using the cobas 4800 HPV test.Methods:
Routine cervical samples collected in our laboratory were analyzed by cobas 4800 HPV test.Results:
A total of 2247 samples from female patients aged 17–79 years were tested. high-risk human papillomavirus was positive in 775 (34.49%) samples. Of these, 641 (82.71%) were single infections and 134 (17.29%) were multiple infections. The positivity rates for HPV 16, HPV 18, and other high-risk human papillomavirus were 10.77%, 2.0%, and 28.08%, respectively. In multiple high-risk human papillomavirus infections, the concomitance of HPV 16 and other high-risk human papillomavirus was more prevalent (13.42%).Conclusion:
Our study showed high prevalence of high-risk human papillomavirus in urban Peru, mainly among young women. In both single and multiple infections other high-risk human papillomavirus were more prevalent than HPV 16 and HPV 18, which might influence vaccine impact in our country. Furthermore, the cobas 4800 HPV test may be considered a useful tool for HPV molecular diagnosis. .Mots clés
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Col de l'utérus
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Infections à papillomavirus
Type d'étude:
Diagnostic_studies
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Etiology_studies
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Prevalence_studies
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Risk_factors_studies
Limites du sujet:
Adult
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Aged
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Female
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Humans
Pays comme sujet:
America do sul
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Peru
langue:
En
Texte intégral:
Braz. j. infect. dis
Thème du journal:
DOENCAS TRANSMISSIVEIS
Année:
2014
Type:
Article