Association among H. pylori virulence markers dupA, cagA and vacA in Brazilian patients
J. venom. anim. toxins incl. trop. dis
;
2004/02/2014.
Article
Dans Anglais
| LILACS
| ID: lil-724676
ABSTRACT
Only a few Helicobacter pylori-infected individuals develop severe gastric diseases and virulence factors of H. pylori appear to be involved in such clinical outcomes. Duodenal ulcer promoting gene A (dupA) is a novel virulence factor of Helicobacter pylori that is associated with duodenal ulcer development and reduced risk for gastric carcinoma in some populations. The aims of the present study were to determine the presence of dupA gene and evaluate the association among dupA and other virulence factors including cagA and vacA in Brazilian patients. Gastric biopsies were obtained from 205 dyspeptic patients (100 children and 105 adults). DNA was extracted and analyzed for the presence of H. pylori and its virulence factors using the polymerase chain reaction method.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Ulcère peptique
/
Virulence
/
Helicobacter pylori
Type d'étude:
Facteurs de risque
Limites du sujet:
Animaux
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
J. venom. anim. toxins incl. trop. dis
Thème du journal:
Toxicologie
Année:
2014
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade do Sagrado Coração/BR
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