Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
Rev. bras. hematol. hemoter
;
36(5): 340-344, Sep-Oct/2014. tab, graf
Article
Dans Anglais
| LILACS
| ID: lil-725673
ABSTRACT
Objective:
The aim of the present study was to characterize sickle cell disease retinopathy in children and teenagers from Bahia, the state in northeastern Brazil with the highest incidence and prevalence of sickle cell disease.Methods:
A group of 51 sickle cell disease patients (36 hemoglobin SS and 15 hemoglobin SC) with ages ranging from 4 to 18 years was studied. Ophthalmological examinations were performed in all patients. Moreover, a fluorescein angiography was also performed in over 10-year-old patients.Results:
The most common ocular lesions were vascular tortuosity, which was found in nine (25%) hemoglobin SS patients, and black sunburst, in three (20%) hemoglobin SC patients. Peripheral arterial closure was observed in five (13.9%) hemoglobin SS patients and in three (13.3%) hemoglobin SC patients. Arteriovenous anastomoses were present in six (16.5%) hemoglobin SS patients and six (37.5%) hemoglobin SC patients. Neovascularization was not identified in any of the patients.Conclusions:
This study supports the use of early ophthalmological examinations in young sickle cell disease patients to prevent the progression of retinopathy to severe disease and further blindness...
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Rétinopathies
/
Enfant
/
Adolescent
/
Drépanocytose SC
/
Drépanocytose
Type d'étude:
Facteurs de risque
Limites du sujet:
Adolescent
/
Enfant
/
Humains
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Rev. bras. hematol. hemoter
Thème du journal:
Hématologie
Année:
2014
Type:
Article
/
descriptif de projet
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Escola Bahiana de Medicina e Saúde Publica/BR
/
Fundação de Hematologia e Hemoterapia do Estado da Bahia/BR
/
Instituto Brasileiro de Oftalmologia e Prevenção da Cegueira/BR
/
Universidade Federal da Bahia/BR
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