Evaluation of the role of ATP-binding cassette transporters as a defence mechanism against temephos in populations of Aedes aegypti
Mem. Inst. Oswaldo Cruz
;
109(7): 964-966, 11/2014. tab
Article
Dans Anglais
| LILACS
| ID: lil-728807
ABSTRACT
The role of ATP-binding cassette (ABC) transporters in the efflux of the insecticide, temephos, was assessed in the larvae of Aedes aegypti. Bioassays were conducted using mosquito populations that were either susceptible or resistant to temephos by exposure to insecticide alone or in combination with sublethal doses of the ABC transporter inhibitor, verapamil (30, 35 and 40 μM). The best result in the series was obtained with the addition of verapamil (40 μM), which led to a 2x increase in the toxicity of temephos, suggesting that ABC transporters may be partially involved in conferring resistance to the populations evaluated.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Téméfos
/
Résistance aux insecticides
/
Transporteurs ABC
/
Aedes
/
Vecteurs insectes
/
Insecticides
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2014
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Federal do Cariri/BR
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