Association between allergic responses and Schistosoma mansoni infection in residents in a low-endemic setting in Brazil
Rev. Soc. Bras. Med. Trop
; 47(6): 770-774, Nov-Dec/2014. graf
Article
Dans En
| LILACS
| ID: lil-732977
Responsable en Bibliothèque :
BR1.1
ABSTRACT
Introduction Schistosomiasis is endemic in 76 countries and territories. Several studies have found an inverse correlation between parasitic disease and the development of allergies. The purpose of the present study was to determine whether infection with Schistosoma mansoni in subjects with a low parasite load is protective against allergy. The final sample consisted of 39 S. mansoni-positive and 52 S. mansoni-negative residents of a small community in northeastern Brazil. Methods All subjects were submitted to the Kato-Katz test, anti-S. mansoni IgG measurement, the prick test for aeroallergens, eosinophil counts and serum IgE measurement. Results Subjects who reacted to one or more antigens in the prick test were considered allergic. Only 7 S. mansoni-positive subjects (17.9%) reacted to one or more antigens, whereas 20 S. mansoni-negative subjects (38.5%) tested positive for allergy. Conclusions Our findings suggest that, in areas of low endemicity, infection with S. mansoni significantly reduces the risk of the development of allergy in subjects with a low parasite load. .
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Schistosoma mansoni
/
Schistosomiase à Schistosoma mansoni
/
Anticorps antihelminthe
/
Allergènes
/
Hypersensibilité immédiate
/
Antigènes d'helminthe
Type d'étude:
Observational_studies
/
Risk_factors_studies
Limites du sujet:
Animals
/
Humans
Pays comme sujet:
America do sul
/
Brasil
langue:
En
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
MEDICINA TROPICAL
Année:
2014
Type:
Article