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Effect of sugarcane biopolymer in vocal fold of rabbits. Comparative study with calcium hydroxyapatite
Vasconcelos, Silvio José de; Leão, Rodrigo Augusto Souza; Bernardino-Araújo, Sidcley; Lira, Mariana Montenegro de Melo; Tsuji, Domingos Hiroshi.
  • Vasconcelos, Silvio José de; University of Sao Paulo. BR
  • Leão, Rodrigo Augusto Souza; University of Sao Paulo. BR
  • Bernardino-Araújo, Sidcley; University of Sao Paulo. BR
  • Lira, Mariana Montenegro de Melo; University of Sao Paulo. BR
  • Tsuji, Domingos Hiroshi; University of Sao Paulo. BR
Acta cir. bras ; 30(3): 186-193, 03/2015. tab, graf
Article Dans Anglais | LILACS | ID: lil-741039
ABSTRACT

PURPOSE:

To compare the inflammatory reaction caused by the injection of a sugarcane biopolymer (SCB) into the vocal fold of rabbits with that caused by calcium hydroxyapatite (CaH).

METHODS:

CaH (Radiesse(r)) and SCB gel were injected respectively into the right and left vocal cords of thirty rabbits. The rabbits were distributed into two equal groups and sacrificed at three and twelve weeks after injection. We then evaluated the intensity of the inflammatory reaction, plus levels of neovascularization, fibrogenesis and inflammatory changes in the vocal mucosa.

RESULTS:

The vocal cords injected with CaH had a stronger inflammatory reaction by giant cells in both study periods. The SCB group had a more intense inflammatory involvement of polymorphonuclear cells three weeks after injection. SCB caused a higher level of neovascularization compared with CaH three weeks after the procedure.

CONCLUSION:

Whereas calcium hydroxyapatite triggers a more intense and lasting inflammatory reaction mediated by giant cells, sugarcane biopolymer causes a greater response from polymorphonuclear leukocytes, as well as higher levels of vneoascularization three weeks after injection. .
Sujets)


Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Tumeurs de la prostate / Calcinose / Interprétation d'images radiographiques assistée par ordinateur / Tomodensitométrie hélicoïdale / Radiothérapie guidée par l'image Type d'étude: Etude diagnostique Limites du sujet: Adulte très âgé / Humains / Mâle langue: Anglais Texte intégral: Acta cir. bras Thème du journal: Chirurgie générale / Procedimentos Cir£rgicos Operat¢rios Année: 2015 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: University of Sao Paulo/BR

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Tumeurs de la prostate / Calcinose / Interprétation d'images radiographiques assistée par ordinateur / Tomodensitométrie hélicoïdale / Radiothérapie guidée par l'image Type d'étude: Etude diagnostique Limites du sujet: Adulte très âgé / Humains / Mâle langue: Anglais Texte intégral: Acta cir. bras Thème du journal: Chirurgie générale / Procedimentos Cir£rgicos Operat¢rios Année: 2015 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: University of Sao Paulo/BR