Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
Mem. Inst. Oswaldo Cruz
;
110(1): 151-153, 03/02/2015. tab, graf
Article
Dans Anglais
| LILACS
| ID: lil-741612
ABSTRACT
The Brazilian Amazon Region is a highly endemic area for hepatitis B virus (HBV). However, little is known regarding the genetic variability of the strains circulating in this geographical region. Here, we describe the first full-length genomes of HBV isolated in the Brazilian Amazon Region; these genomes are also the first complete HBV subgenotype D3 genomes reported for Brazil. The genomes of the five Brazilian isolates were all 3,182 base pairs in length and the isolates were classified as belonging to subgenotype D3, subtypes ayw2 (n = 3) and ayw3 (n = 2). Phylogenetic analysis suggested that the Brazilian sequences are not likely to be closely related to European D3 sequences. Such results will contribute to further epidemiological and evolutionary studies of HBV.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Transduction du signal
/
Mouvement cellulaire
/
Carcinome hépatocellulaire
/
Inhibiteur tissulaire de métalloprotéinase-1
/
Matrix metalloproteinase 9
/
Tumeurs du foie
Limites du sujet:
Humains
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2015
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Fiocruz/BR
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