Evaluation of the predictive indices for candidemia in an adult intensive care unit
Rev. Soc. Bras. Med. Trop
;
48(1): 77-82, jan-feb/2015. tab, graf
Article
Dans Anglais
| LILACS
| ID: lil-742967
ABSTRACT
INTRODUCTION:
To evaluate predictive indices for candidemia in an adult intensive care unit (ICU) and to propose a new index.METHODS:
A prospective cohort study was conducted between January 2011 and December 2012. This study was performed in an ICU in a tertiary care hospital at a public university and included 114 patients staying in the adult ICU for at least 48 hours. The association of patient variables with candidemia was analyzed.RESULTS:
There were 18 (15.8%) proven cases of candidemia and 96 (84.2%) cases without candidemia. Univariate analysis revealed the following risk factors parenteral nutrition, severe sepsis, surgical procedure, dialysis, pancreatitis, acute renal failure, and an APACHE II score higher than 20. For the Candida score index, the odds ratio was 8.50 (95% CI, 2.57 to 28.09); the sensitivity, specificity, positive predictive value, and negative predictive value were 0.78, 0.71, 0.33, and 0.94, respectively. With respect to the clinical predictor index, the odds ratio was 9.45 (95%CI, 2.06 to 43.39); the sensitivity, specificity, positive predictive value, and negative predictive value were 0.89, 0.54, 0.27, and 0.96, respectively. The proposed candidemia index cutoff was 8.5; the sensitivity, specificity, positive predictive value, and negative predictive value were 0.77, 0.70, 0.33, and 0.94, respectively.CONCLUSIONS:
The Candida score and clinical predictor index excluded candidemia satisfactorily. The effectiveness of the candidemia index was comparable to that of the Candida score. .
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Isolement social
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Consommation d'alcool
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Cause de décès
/
Situation de famille
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Maladies alcooliques du foie
Type d'étude:
Etude d'étiologie
/
Etude d'incidence
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Étude observationnelle
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Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Europe
langue:
Anglais
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2015
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade de São Paulo/BR
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