Your browser doesn't support javascript.
loading
Serum concentrations of brain-derived neurotrophic factor and mental disorders in imprisoned women
Dotta-Panichi, Renata M.; Bins, Helena D.; Tramontina, Juliana F.; Ceresér, Keila M.; Aguiar, Bianca W. de; Paz, André C.; Taborda, José G..
  • Dotta-Panichi, Renata M.; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA). Graduate Program in Health Sciences. Porto Alegre. BR
  • Bins, Helena D.; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA). Graduate Program in Health Sciences. Porto Alegre. BR
  • Tramontina, Juliana F.; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA). Graduate Program in Health Sciences. Porto Alegre. BR
  • Ceresér, Keila M.; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA). Graduate Program in Health Sciences. Porto Alegre. BR
  • Aguiar, Bianca W. de; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA). Graduate Program in Health Sciences. Porto Alegre. BR
  • Paz, André C.; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA). Graduate Program in Health Sciences. Porto Alegre. BR
  • Taborda, José G.; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA). Graduate Program in Health Sciences. Porto Alegre. BR
Braz. J. Psychiatry (São Paulo, 1999, Impr.) ; 37(2): 113-120, 12/05/2015. tab, graf
Article Dans Anglais | LILACS | ID: lil-748975
ABSTRACT

Objective:

Mental disorders and early trauma are highly prevalent in female inmates. Brain-derived neurotrophic factor (BDNF) plays an important role in learning, memory processes, and mood regulation. The aim of this study was to evaluate the relationship between serum BDNF levels and mental disorders among imprisoned women as compared with age- and education-matched controls.

Methods:

A consecutively recruited sample of 18 female prisoners with mental disorders was assessed for sociodemographic, criminal, and clinical variables using standardized instruments, the Mini International Neuropsychiatric Interview Plus (MINI Plus), and serum BDNF levels.

Results:

High rates of childhood sexual abuse and posttraumatic stress disorder (PTSD) were found in the group of forensic patients. Serum BDNF levels in the forensic group did not differ from those of healthy controls, and were significantly higher when compared with those of women with mental disorders hospitalized in a general hospital.

Conclusion:

Elevated serum BDNF levels were found in imprisoned women. The results of this study may suggest neurobiological mechanisms similar to those seen in previous clinical and preclinical studies showing the involvement of BDNF in the pathophysiology of PTSD. .
Sujets)


Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Prisonniers / Troubles de stress post-traumatique / Facteur neurotrophique dérivé du cerveau Type d'étude: Étude observationnelle / Étude de prévalence / Facteurs de risque Limites du sujet: Adulte / Femelle / Humains Pays comme sujet: Amérique du Sud / Brésil langue: Anglais Texte intégral: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Thème du journal: Psychiatrie Année: 2015 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)/BR

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS


Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Prisonniers / Troubles de stress post-traumatique / Facteur neurotrophique dérivé du cerveau Type d'étude: Étude observationnelle / Étude de prévalence / Facteurs de risque Limites du sujet: Adulte / Femelle / Humains Pays comme sujet: Amérique du Sud / Brésil langue: Anglais Texte intégral: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Thème du journal: Psychiatrie Année: 2015 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)/BR