Reacción por drogas con eosinofilia y síntomas sistémicos (síndrome de DRESS): Estudio retrospectivo de nueve casos / Dress syndrome: Report of nine cases
Rev. méd. Chile
;
143(5): 577-583, ilus, tab
Article
Dans Espagnol
| LILACS
| ID: lil-751702
ABSTRACT
Background:
DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs. It is characterized by a polymorphic disseminated eruption with fever and multiple organ dysfunction.Aim:
To report the etiology, characteristics, treatment, prognosis, and follow up of patients with DRESS Syndrome admitted to a clinical hospital. Material andMethods:
Review of medical records of patients admitted for drug reactions, selecting those patients complying with clinical criteria for DRESS Syndrome. Drugs used during three months prior to the onset of symptoms were evaluated as possible causes of the disease.Results:
Nine patients aged 16 to 68 years (six males) complied with the clinical criteria for the disease. The causative medications were carbamazepine in three patients, phenytoin in three, antituberculous drugs in two and amoxicillin in one. All were treated with systemic steroids with a complete clinical resolution.Conclusions:
DRESS syndrome is usually underdiagnosed and has a good response to systemic steroids.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Dexaméthasone
/
Prednisone
/
Syndrome d'hypersensibilité médicamenteuse
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Espagnol
Texte intégral:
Rev. méd. Chile
Thème du journal:
Médicament
Année:
2015
Type:
Article
Pays d'affiliation:
Mexique
Institution/Pays d'affiliation:
Universidad Autónoma de Nuevo León/MX
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