Resistance of dialyzed patients to erythropoietin
Rev. bras. hematol. hemoter
;
37(3): 190-197, May-Jun/2015. tab
Article
Dans Anglais
| LILACS
| ID: lil-752543
ABSTRACT
Resistance to recombinant human erythropoietin is a common condition in dialyzed patients with chronic kidney disease and is associated with more hospitalizations, increased mortality and frequent blood transfusions. The main cause of hyporesponsiveness to recombinant human erythropoietin in these patients is iron deficiency. However, a high proportion of patients does not respond to treatment, even to the use of intravenous iron, which indicates the presence of other important causes of resistance. In addition to the iron deficiency, the most common causes of resistance include inflammation, infection, malnutrition, inadequate dialysis, and hyperparathyroidism, although other factors may be associated. In the presence of adequate iron stores, other causes should be investigated and treated appropriately.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Érythropoïétine
/
Dialyse rénale
/
Transplantation rénale
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Rev. bras. hematol. hemoter
Thème du journal:
Hématologie
Année:
2015
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Hospital Felício Rocho/BR
/
Universidade Federal de Minas Gerais/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS