Decline in semen quality among infertile men in Brazil during the past 10 years
Int. braz. j. urol
;
41(4): 757-763, July-Aug. 2015. tab, graf
Article
Dans Anglais
| LILACS
| ID: lil-763061
ABSTRACT
ABSTRACTPurpose:
To investigate whether the semen quality of men undergoing conventional semen analysis is deteriorating over time.Materials andMethods:
We analyzed and compared the sperm count, motility and morphology of 2300 semen samples provided by males undergoing conventional seminal analysis, from years 2000 to 2002 and 2010 to 2012. The incidences of severe oligozoospermia and azoospermia over time were also compared.Results:
A total of 764 sperm samples were analyzed in 2000-2002 and 1536 in 20102012. Over time, the mean sperm concentration/ml decreased significantly from 61.7 million in 2000-2002 to 26.7 million in 2010-2012 (R2=11.4%, p<0.001), the total sperm concentration decreased significantly from 183.0 million to 82.8 million (R2=11.3%, p<0.001), and the percentage of normal forms decreased significantly from 4.6% to 2.7% (R2=9.8%, p<0.001). The incidence of severe oligozoospermia significantly increased from 15.7% to 30.3% (OR 1.09, p<0.001) and the incidence of azoospermia increased from 4.9% to 8.5% (OR 1.06, p=0.001).Conclusions:
This study demonstrated a significant time-related decline in semen quality of infertile patients. This finding might have implications on fertility and emphasizes the need for further studies addressing subject's life-style in order to find and reduce the causative agents. Future prospective and multicenter studies including representative samples of the general population are needed to confirm whether semen quality is really declining.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Numération des spermatozoïdes
/
Analyse du sperme
/
Infertilité masculine
Type d'étude:
Etude diagnostique
/
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Int. braz. j. urol
Thème du journal:
Urologie
Année:
2015
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Centro de Fertilização Assistida/BR
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