Expression of Sphingosine-1-phosphate (S1P) on the cerebral vasospasm after subarachnoid hemorrhage in rabbits
Acta cir. bras
;
30(10): 654-659, graf
Article
Dans Anglais
| LILACS
| ID: lil-764395
ABSTRACT
PURPOSE:
To demonstrate the relationship between of sphingosine-1-phosphate (S1P) expression and subarachnoid hemorrhage (SAH).METHODS:
The basilar arteries from a "double-hemorrhage" rabbit model of SAH were used to investigate the relation between S1P expression and SAH. Various symptoms, including blood clots, basilar artery cross-sectional area, and S1P phosphatase expression were measured at day 3, 5, 7, 9.RESULTS:
The expression of S1P was enhanced in the cerebral vasospasm after subarachnoid hemorrhage in the rabbits. And S1P expression was consistent with the basilar artery cross-sectional area changes at day 3, 5, 7, 9.CONCLUSION:
Sphingosine-1-phosphate expression in the cerebral arterial may be a new indicator in the development of cerebral vasospasm after subarachnoid hemorrhage and provide a new therapeutic method for SAH.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Sphingosine
/
Hémorragie meningée
/
Lysophospholipides
/
Vasospasme intracrânien
Type d'étude:
Etude d'étiologie
/
Étude pronostique
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Acta cir. bras
Thème du journal:
Chirurgie générale
/
Procedimentos Cir£rgicos Operat¢rios
Année:
2015
Type:
Article
Pays d'affiliation:
Chine
Institution/Pays d'affiliation:
Wuhan University/CN
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