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Mean platelet volume in patients with retinal artery occlusion / Volume médio de plaquetas em pacientes com oclusão da artéria da retina
Şahin, Muhammed; Şahin, Alparslan; Yüksel, Harun; Türkcü, Fatih Mehmet; Yıldırım, Adnan.
Affiliation
  • Şahin, Muhammed; Dicle University. School of Medicine. Departments of Ophthalmology. Diyarbakir. TR
  • Şahin, Alparslan; Dicle University. School of Medicine. Departments of Ophthalmology. Diyarbakir. TR
  • Yüksel, Harun; Dicle University. School of Medicine. Departments of Ophthalmology. Diyarbakir. TR
  • Türkcü, Fatih Mehmet; Dicle University. School of Medicine. Departments of Ophthalmology. Diyarbakir. TR
  • Yıldırım, Adnan; Dicle University. School of Medicine. Departments of Ophthalmology. Diyarbakir. TR
Arq. bras. oftalmol ; Arq. bras. oftalmol;79(1): 12-14, Jan.-Feb. 2016. tab
Article de En | LILACS | ID: lil-771902
Bibliothèque responsable: BR1.1
ABSTRACT
ABSTRACT

Purpose:

The aim of this study was to investigate the mean platelet volume (MPV) of patients with retinal artery occlusion (RAO).

Methods:

Thirty-seven patients diagnosed with RAO and 32 control subjects were included in this retrospective study. Retinal artery occlusion was diagnosed on the basis of clinical examination and fundus fluorescein angiography. All participants underwent complete ocular examination, and MPV, hematocrit, hemoglobin, and platelet counts were recorded. RAO patient data were compared with those of the control subjects.

Results:

Patients with RAO had significantly higher MPV values (7.96 ± 1.2 fL) compared with control subjects (7.33 ± 0.7 fL, p<0.001). No significant difference was found with regard to platelet count between the RAO group and the control group (262 ± 70.1 × 109/L and 251 ± 56.6 × 109/L, respectively, p=0.50). MPV was an independent predictor of RAO [odds ratio (OR)=0.50; 95% confidence interval (CI)=0.28-0.89; p=0.019).

Conclusions:

Our results demonstrated that MPV values were significantly higher in patients with RAO, suggesting that larger platelets may contribute to the pathogenesis of the RAOs.
RESUMO
RESUMO

Objetivo:

O objetivo deste estudo foi investigar o volume plaquetário médio (MPV) de pacientes com oclusão da artéria da retina (RAO).

Métodos:

Trinta e sete pacientes com diagnóstico de RAO e 32 indivíduos do grupo controle foram incluídos neste estudo retrospectivo. A oclusão da artéria da retina foi diagnosticada com base em exame clínico e angiofluoresceinografia. Todos os participantes foram submetidos ao exame ocular completo. MPV, hematócrito, hemoglobina e contagem de plaquetas dos participantes foram registrados. Os dados dos pacientes com RAO foi comparado com os de sujeitos do grupo controle.

Resultados:

Pacientes com RAO apresentaram valores significativamente mais elevados MPV (7,96 ± 1,2 fL) em comparação aos indivíduos do grupo controle (7,33 ± 0,7 fL) (p<0,001). Nenhuma diferença significativa foi encontrada no número de plaquetas entre os grupos RAO e controle (262 ± 70,1 109/L and 251 ± 56,6 109/L, respectivamente, p=0,50). MPV foi um preditor independente de RAO (odds ratio (OR)=0,50; intervalo de confiança de 95% (IC)=0,28-0,89; p=0,019).

Conclusões:

Os resultados demonstraram que os valores de MPV foram significativamente maiores nos pacientes com RAO, sugerindo que plaquetas maiores podem contribuir na patogênese da RAO.
Sujet(s)
Mots clés

Texte intégral: 1 Indice: LILACS Sujet Principal: Occlusion artérielle rétinienne / Volume plaquettaire moyen Type d'étude: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limites du sujet: Adult / Aged / Female / Humans / Male langue: En Texte intégral: Arq. bras. oftalmol Thème du journal: OFTALMOLOGIA Année: 2016 Type: Article

Texte intégral: 1 Indice: LILACS Sujet Principal: Occlusion artérielle rétinienne / Volume plaquettaire moyen Type d'étude: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limites du sujet: Adult / Aged / Female / Humans / Male langue: En Texte intégral: Arq. bras. oftalmol Thème du journal: OFTALMOLOGIA Année: 2016 Type: Article