Effects of undernutrition during suckling and of post-training ß-endorphin administration on avoidance performances of adult rats
Braz. j. med. biol. res
;
20(6): 731-40, 1987. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-77425
ABSTRACT
1. The effects of undernutrition during suckling and of post-training ß-endorphin administration on avoidance task were invstigated in adult rats. 2. young rats were undernourished from delivery until weaning (21 days) by feeding their mothers a diet conatining 8% protein (w/w). Mothers of well-nourished rats were fed a 20% protein diet. After weaning, both groups of rats were fed a 20% protein diet until 90-120 days if age, when they were subjected to behavioral sessions. 3. Acquistion was measured in training sessions and retention in test sessions 24 h after training. Beta-endorphin or salina (control) was injected ip immdiately after training. Rats were subjected to shuttle and step-down inhibitory avoidance sessions using footshock of 0.2 or 0.8 mA intensity. 4. Undernutrition during suckling caused hyperreactivity to 0.2 mA footshocks. Beta-endorphin caused amnesia to shuttle avoidance task only in normal rats trained with 0.8 mA. Foor-shocks. In the step-down inhibitory avoidance task, ß-endorphin was amnesic only for normal rats and only for 0.2-mA footshocks. Beta-endorphin was not amnesic in undernourished rats
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Indice:
LILAS (Amériques)
Sujet Principal:
/
Bêta-Endorphine
/
Malnutrition protéinocalorique
/
Réaction de fuite
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Braz. j. med. biol. res
Thème du journal:
Biologie
/
Médicament
Année:
1987
Type:
Article
/
descriptif de projet
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