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Interview-based assessment of cognition is a strong predictor of quality of life in patients with schizophrenia and severe negative symptoms
Cruz, Breno F; Resende, Camilo B. de; Carvalhaes, Carolina F; Cardoso, Clareci S; Teixeira, Antonio L; Keefe, Richard S; Rocha, Fábio L; Salgado, João V.
  • Cruz, Breno F; Universidade Federal de Minas Gerais (UFMG). Instituto de Ciências Biológicas. Programa de Pós-Graduação em Neurociências. Belo Horizonte. BR
  • Resende, Camilo B. de; Universidade Federal de Minas Gerais (UFMG). Instituto de Ciências Biológicas. Programa de Pós-Graduação em Neurociências. Belo Horizonte. BR
  • Carvalhaes, Carolina F; Universidade Federal de Minas Gerais (UFMG). Instituto de Ciências Biológicas. Programa de Pós-Graduação em Neurociências. Belo Horizonte. BR
  • Cardoso, Clareci S; Universidade Federal de Minas Gerais (UFMG). Instituto de Ciências Biológicas. Programa de Pós-Graduação em Neurociências. Belo Horizonte. BR
  • Teixeira, Antonio L; Universidade Federal de Minas Gerais (UFMG). Instituto de Ciências Biológicas. Programa de Pós-Graduação em Neurociências. Belo Horizonte. BR
  • Keefe, Richard S; Universidade Federal de Minas Gerais (UFMG). Instituto de Ciências Biológicas. Programa de Pós-Graduação em Neurociências. Belo Horizonte. BR
  • Rocha, Fábio L; Universidade Federal de Minas Gerais (UFMG). Instituto de Ciências Biológicas. Programa de Pós-Graduação em Neurociências. Belo Horizonte. BR
  • Salgado, João V; Universidade Federal de Minas Gerais (UFMG). Instituto de Ciências Biológicas. Programa de Pós-Graduação em Neurociências. Belo Horizonte. BR
Braz. J. Psychiatry (São Paulo, 1999, Impr.) ; 38(3): 216-221, July-Sept. 2016. tab, graf
Article Dans Anglais | LILACS | ID: lil-792742
ABSTRACT

Objective:

To analyze the correlation between quality of life, symptoms, and cognition assessed by the interview-based Schizophrenia Cognition Rating Scale (SCoRS).

Methods:

Seventy-nine outpatients diagnosed with schizophrenia were evaluated with the Quality of Life Scale – Brazilian version (QLS-BR), the SCoRS, and symptoms scales (Positive and Negative Syndrome Scale [PANSS]). After determining the potential explanatory variables using Spearman’s correlation and Student’s t test results, we ran simple, multivariate, and decision-tree regression analyses to assess the impact of SCoRS and PANSS ratings on mean overall quality of life.

Results:

Cognitive deficits and negative symptoms were the best predictors of quality of life. A low degree of negative symptoms (PANSS negative < 11) was a strong predictor of better quality of life (QLS ∼ 75), regardless of SCoRS rating. Among participants with more severe negative symptoms, elevated cognitive impairment (interviewer SCoRS ∼ 44) was a predictor of worse quality of life (QLS ∼ 44).

Conclusions:

Cognitive impairment determined by interview-based assessment seems to be a strong predictor of quality of life in subjects with severe negative symptoms. These results support the usefulness of SCoRS for cognitive assessment that is relevant to the everyday life of patients with schizophrenia.
Sujets)


Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Échelles d&apos;évaluation en psychiatrie / Qualité de vie / Schizophrénie / Dysfonctionnement cognitif Type d'étude: Etude diagnostique / Étude pronostique / Recherche qualitative / Facteurs de risque Limites du sujet: Adulte / Femelle / Humains / Mâle Pays comme sujet: Amérique du Sud / Brésil langue: Anglais Texte intégral: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Thème du journal: Psychiatrie Année: 2016 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade Federal de Minas Gerais (UFMG)/BR

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Échelles d&apos;évaluation en psychiatrie / Qualité de vie / Schizophrénie / Dysfonctionnement cognitif Type d'étude: Etude diagnostique / Étude pronostique / Recherche qualitative / Facteurs de risque Limites du sujet: Adulte / Femelle / Humains / Mâle Pays comme sujet: Amérique du Sud / Brésil langue: Anglais Texte intégral: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Thème du journal: Psychiatrie Année: 2016 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade Federal de Minas Gerais (UFMG)/BR