Peripheral immune response in albino rats following cerebroventricular and intraperitoneal antigen challenge.
Indian J Physiol Pharmacol
;
1995 Oct; 39(4): 354-60
Article
Dans Anglais
| IMSEAR
| ID: sea-107051
ABSTRACT
Success in neural tissue transplants at central nervous system suggest that the site may be immunologically privileged. However, this experimental study in which an antigen (Sheep Red Blood Cells) was administered into the third ventricle does not support the above concept. The antibody titre and soluble immune complex levels seen in these animals are similar to the levels seen in animals immunized with the same amount of antigen through the intraperitoneal route. Intraventricular immunization is rather a more potent modulator in decreasing the total WBC count (P < 0.05) and neutrophils (P < 0.001). Further a marked increase in lymphocytes (P < 0.01) in peripheral blood was observed in these animals. Intraventricular immunization also increased the killing power (NBT reduction) of the neutrophils (P < 0.05).
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Phagocytose
/
Rats
/
Ovis
/
Ventricules cérébraux
/
Rat Wistar
/
Érythrocytes
/
Injections péritoneales
/
Injections ventriculaires
/
Numération des leucocytes
/
Animaux
langue:
Anglais
Texte intégral:
Indian J Physiol Pharmacol
Année:
1995
Type:
Article
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