Calcium-transporters in myocardial cells.
Indian J Physiol Pharmacol
;
2006 Apr-Jun; 50(2): 99-113
Article
Dans Anglais
| IMSEAR
| ID: sea-108723
ABSTRACT
This is a concise review of important calcium-transporters on the sarcolemma and organellar membranes of myocardial cells, and their functional roles in cell physiology. It briefly addresses L and T type calcium channels, store-operated calcium channel (SOC), sodium-calcium exchanger (NCX), and the plasma membrane calcium ATPase (PMCA) on the sarcolemma, ryanodine receptor (RyR), IP3 receptor (IP3R) and the sarcoplasmic reticulum (SR) calcium ATPase (SAERCA) on the SR membrane and their contributions to contraction and rhythm-generation. Several agonists and blockers for every transporter that are commonly used in research, and those with therapeutic applications have also been discussed.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sarcolemme
/
Humains
/
Canaux calciques
/
Calcium-Transporting ATPases
/
Récepteurs cytoplasmiques et nucléaires
/
Canal de libération du calcium du récepteur à la ryanodine
/
Échangeur sodium-calcium
/
Canaux calciques de type L
/
Canaux calciques de type T
/
Transporteurs de cations
langue:
Anglais
Texte intégral:
Indian J Physiol Pharmacol
Année:
2006
Type:
Article
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