Anti-malarial activity of Eclipta alba against Plasmodium berghei infection in mice.
Article
Dans Anglais
| IMSEAR
| ID: sea-112199
ABSTRACT
The anti-malarial activity of Eclipta alba leaves extract was evaluated against Plasmodium'berghei ANKA strain in mice. A standard inoculum of 1 x 10(6) infected erythrocytes was used. The methanolic leaf extract (250-750 mg/kg) produced a dose-dependant chemosupression or schizontocidal effect during early and established infection and high mean survival time (m.s.t.) values particularly in the group administered 750 mg/kg/day of extract. The plant extract also exhibited repository activity. The results of the preliminary studies carried out with E. alba are encouraging, which can be exploited in malaria therapy.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Plasmodium berghei
/
Humains
/
Mâle
/
Extraits de plantes
/
Résultat thérapeutique
/
Tests de sensibilité parasitaire
/
Eclipta
/
Modèles animaux de maladie humaine
/
Animaux
/
Paludisme
langue:
Anglais
Année:
2007
Type:
Article
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