Conscious sedation--an artist's science! An Indian experience with midazolam.
J Indian Soc Pedod Prev Dent
;
2006 Mar; 24(1): 7-14
Article
Dans Anglais
| IMSEAR
| ID: sea-114973
ABSTRACT
The present study was undertaken to evaluate Midazolam as a Paediatric conscious sedative agent for a routine Indian dental setup and to compare its efficacy and safety when administered by intranasal and intramuscular routes, at a dosage of 0.2 mg/kg body weight. The present study was accomplished in two phases Phase 1 Preliminary dose finding pilot study on 10 children. Phase 2 Single dose, randomized parallel clinical trial on 40 children between the ages of 2 and 5 years. These children were randomly assigned to two groups consisting of 20 subjects each. Group M, received Midazolam intramuscularly, while Group N received Midazolam intranasally. Both the intranasal and intramuscular groups showed highly significant decrease in crying levels, motor movements and sensory perception levels, post-sedation (P P < 0.001). Midazolam could be safely and successfully employed by intranasal and intramuscular routes for Paediatric conscious sedation in a routine dental setup with basic facilities at a dosage of 0.2 mg/ kg body weight. Whenever the clinical situation warrants a faster action, peak and recovery, the intranasal route should be the obvious choice.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sécurité
/
Éternuement
/
Facteurs temps
/
Vigilance
/
Poids
/
Midazolam
/
Réveil anesthésique
/
Femelle
/
Humains
/
Mâle
Type d'étude:
Essai clinique contrôlé
langue:
Anglais
Texte intégral:
J Indian Soc Pedod Prev Dent
Thème du journal:
Dentistry
Année:
2006
Type:
Article
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