Langerhans' cell histiocytosis - A Case Report.

ABSTRACT

Langerhan's histiocytosis was formerly known as histiocytosis X and refers to a group of conditions characterized by the uncontrolled stimulation and proliferation of a normal antigen-processing cell, the Langerhan's cell. Mandibular involvement associated with LCH is uncommon in a young child. Most reports describing bone involvements in LCH have mainly referred to male subjects over 20 years of age. The purpose of this report is to describe a case of multifocal bony LCH with mandibular involvement in a 8 year old girl and to discuss the appropriate management of such a case.