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Progressive systemic sclerosis (scleroderma), carcinoma breast and valvular heart disease: an unusual combination.
J Postgrad Med ; 2000 Jul-Sep; 46(3): 181-3
Article de En | IMSEAR | ID: sea-116702
Systemic sclerosis is a multi system disorder characterised by fibrosis of skin and internal organs. There are reports of relation between cancer and polymyositis/dermatomyositis, but no overall association with systemic sclerosis. Reports of the coexistence of cancer and systemic sclerosis, however, emphasise a close temporal relation in their occurrence. Cardiac involvement in the form of myocardial fibrosis and pericarditis occurs frequently in systemic sclerosis, while valvular involvement has been reported only sporadically. We report a patient, admitted for adenocarcinoma of left breast who was found to have features of systemic sclerosis, pulmonary hypertension, gangrene of toes, and stenotic mitral valve disease. The possible mechanisms of the coincidence of the three disorders are discussed.
Sujet(s)
Texte intégral: 1 Indice: IMSEAR Sujet Principal: Sclérodermie systémique / Tumeurs du sein / Femelle / Humains / Études de suivi / Carcinome canalaire du sein / Appréciation des risques / Adulte d'âge moyen / Insuffisance mitrale Type d'étude: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies langue: En Texte intégral: J. postgrad. med Année: 2000 Type: Article
Texte intégral: 1 Indice: IMSEAR Sujet Principal: Sclérodermie systémique / Tumeurs du sein / Femelle / Humains / Études de suivi / Carcinome canalaire du sein / Appréciation des risques / Adulte d'âge moyen / Insuffisance mitrale Type d'étude: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies langue: En Texte intégral: J. postgrad. med Année: 2000 Type: Article