Guillain-Barré syndrome: association with Campylobacter jejuni and Mycoplasma pneumoniae infections in India.
Article
Dans Anglais
| IMSEAR
| ID: sea-119203
ABSTRACT
BACKGROUND:
Guillain-Barré syndrome is the most common cause of acute neuromuscular paralysis and is considered a post-infectious disease.METHODS:
Twenty patients with Guillain-Barré syndrome admitted to the Neurosciences Centre at the All India Institute of Medical Sciences from November 1997 to August 1998 were investigated for evidence of antecedent infections. This case-control study included 2 controls for each patient, one a household control and the other an age- and sex-matched hospital control suffering from a neurological illness other than Guillain-Barré syndrome. Evidence of recent Campylobacter jejuni infection was investigated by culture and serology, and for Mycoplasma pneumoniae by serology.RESULTS:
There was evidence of recent C. jejuni infection in 35% of the patients compared with 25% of household controls and none of the hospital controls. M. pneumoniae infection was seen in 50% of patients compared with 25% of household controls and 15% of hospital controls. About one-third of the patients (30%) had evidence of both infections. The association of both infections in patients was found to be statistically significant as compared to hospital controls.CONCLUSION:
C. jejuni and M. pneumoniae may be important antecedent illnesses in patients with Guillain-Barré syndrome in India.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Pneumopathie à mycoplasmes
/
Sujet âgé
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Femelle
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Humains
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Mâle
/
Infections à Campylobacter
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Études cas-témoins
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Campylobacter jejuni
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Adolescent
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Adulte
Type d'étude:
Étude observationnelle
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Facteurs de risque
Pays comme sujet:
Asie
langue:
Anglais
Année:
2006
Type:
Article
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