Adverse drug reactions among inpatients in a north Indian referral hospital.
Article
Dans Anglais
| IMSEAR
| ID: sea-119279
ABSTRACT
BACKGROUND:
Monitoring spontaneous adverse drug reactions is one of the epidemiological methods for assessing the safety of drugs in a hospital setting.METHODS:
Data on adverse drug reactions (ADRs) were collected over a 3-year period among inpatients in a north Indian referral hospital using the spontaneous ADR monitoring system.RESULTS:
A total of 317 ADRs were reported. Cutaneous reactions (38.8%) and gastrointestinal disturbances (28.4%) made up a large proportion of reported ADRs. Antimicrobial agents, including those used for antituberculosis therapy, were responsible for 47.3% of the events. Radiocontrast dyes, and antineoplastic and psychoactive agents were the other important drugs causing ADRs. No age- or sex-related differences were found in the overall rate of ADRs, though toxic epidermal necrolysis was more frequent in the elderly.CONCLUSION:
The pattern of ADRs and drugs involved were largely similar to those reported in the western literature.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Préparations pharmaceutiques
/
Enfant
/
Incidence
/
Facteurs de risque
/
Systèmes de signalement des effets indésirables des médicaments
/
Traitement médicamenteux
Type d'étude:
Etude d'étiologie
/
Etude d'incidence
/
Étude pronostique
/
Facteurs de risque
Pays comme sujet:
Asie
langue:
Anglais
Année:
2000
Type:
Article
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