The treatment of kala-azar during pregnancy.
Article
Dans Anglais
| IMSEAR
| ID: sea-119737
ABSTRACT
BACKGROUND. Kala-azar in pregnant women is difficult to treat because for them the two commonly used drugs, sodium stibogluconate and pentamidine, are not considered safe. We assessed the effect of amphotericin B on pregnancy, on the foetus and kala-azar. METHODS. Five pregnant women were administered amphotericin B at a dose of 1 mg/kg body weight daily starting with 0.5 mg/kg body weight till a total dose of 20 mg/kg body weight was given. The progress of pregnancy was monitored ultrasonographically and the mothers and children were followed for six months. RESULTS. All the 5 women were cured of the disease and there was no harmful effect on the children. CONCLUSION. Amphotericin B cures kala-azar during pregnancy with no harmful effects on the foetus.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Femelle
/
Humains
/
Grossesse
/
Amphotéricine B
/
Complications parasitaires de la grossesse
/
Adulte
/
Leishmaniose viscérale
langue:
Anglais
Année:
1993
Type:
Article
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