Role of pleural fluid cholesterol in differentiating transudative from exudative pleural effusion.
Article
Dans Anglais
| IMSEAR
| ID: sea-119914
ABSTRACT
BACKGROUND:
Pleural fluid cholesterol has been reported to be useful in distinguishing between transudative and exudative pleural effusion. However, the difference in lipid profile between tubercular and non-tubercular pleural effusion has not been studied.METHODS:
The lipid profile of pleural fluid in 50 patients with exudative (25 tubercular and 25 non-tubercular) and 25 with transudative effusion was studied. The diagnosis was based on clinical criteria and/or a positive diagnosis from another site.RESULTS:
The criteria that best identified an exudative pleural effusion were pleural fluid cholesterol > or = 60 mg/dl, pleural fluid to serum cholesterol ratio > or = 0.4, pleural fluid triglyceride > or = 40 mg/dl and pleural fluid to serum triglyceride ratio > or = 0.3. Pleural fluid cholesterol had a sensitivity of 88% and a specificity of 100% for exudates with an accuracy of 92%. Pleural fluid to serum cholesterol ratio had a sensitivity of 98% and a specificity of 84%. These results were superior to the criteria proposed by Light et al. (sensitivity 98% and specificity 80%).CONCLUSION:
Pleural fluid cholesterol estimation is an effective and cost-efficient method of differentiating exudative from transudative pleural effusion. The lipid profile does not help in diagnosing tubercular effusion.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Épanchement pleural
/
Femelle
/
Humains
/
Mâle
/
Cholestérol
/
Sensibilité et spécificité
/
Adulte
/
Exsudats et transsudats
/
Adulte d'âge moyen
Type d'étude:
Etude diagnostique
/
Étude pronostique
langue:
Anglais
Année:
2003
Type:
Article
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