Studies on skeletal muscle biopsies in endemic skeletal fluorosis.
Neurol India
;
2000 Jun; 48(2): 187-8
Article
Dans Anglais
| IMSEAR
| ID: sea-121443
ABSTRACT
Neurological manifestations of skeletal fluorosis have been attributed to compressive radiculomyelopathy. Experimental fluorosis has shown evidence of myopathic changes. Data on human muscle pathology is very scanty. This study included 22 patients with established osteofluorosis. 16 of them showed only EMG changes of neurogenic muscle disease. Histochemistry and histopathology of muscle biopsies showed features of muscle atrophy, evidenced by 'type I' atrophy and 'type I' grouping. No myopathic changes were observed. It may be concluded that the primary changes are related to the nerve, with muscle being affected secondarily. There was no evidence of any primary muscle pathology due to fluorosis.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Maladies osseuses
/
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Adenosine triphosphatases
/
Muscles squelettiques
/
Adulte
/
Maladies endémiques
/
Intoxication au fluorure
langue:
Anglais
Texte intégral:
Neurol India
Année:
2000
Type:
Article
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