The influence of age in peripheral facial palsy on brainstem reflex excitability.
Neurol India
;
2005 Sep; 53(3): 318-22; discussion 322
Article
Dans Anglais
| IMSEAR
| ID: sea-121524
ABSTRACT
BACKGROUND:
Neuronal plasticity is expected to be different at different ages and adaptive changes developing after peripheral facial palsy (PFP) may provide a clue in this respect.AIMS:
To investigate the difference in the reorganization developing after facial nerve damage between patients who developed PFP at childhood-youth and middle-old age. PATIENTS ANDMETHODS:
Twenty-two patients were divided into two groups according to the age-at-onset of PFP; young (PFP 1), and elderly (PFP 2). Two age-matched control groups (C 1 and C 2) comprised of 32 healthy subjects were included in the study. The latency, R(2) area, and recovery of the R(2) area of the blink reflex were investigated. STATISTICALANALYSIS:
ANOVA and Bonferroni tests were used.RESULTS:
The R(2) areas were significantly greater on the intact side of the PFP 1 group as compared to that in the control group ( P =0.012). The recovery of R2 component was significantly enhanced on the symptomatic (P = 0.027), and intact (P = 0.041) sides in PFP 1 as compared to that in the C 2 group at the stimulus interval of 600 ms. Significant enhanced recovery was noted at 200 ms stimulus interval on the symptomatic side of the two PFP groups (PFP 1, P = 0.05 and PFP 2, P = 0.025) and on the intact side of the PFP 1 group (P =0.035) as compared to that in the control groups.CONCLUSION:
Young age-at-onset of PFP is associated with more prominent excitability changes developing at the neuronal and interneuronal level.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Temps de réaction
/
Réflexe
/
Tronc cérébral
/
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Vieillissement
/
Enfant
/
Études rétrospectives
Type d'étude:
Étude observationnelle
langue:
Anglais
Texte intégral:
Neurol India
Année:
2005
Type:
Article
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