Two children with invasive gastrointestinal aspergillosis.

ABSTRACT

We report two immunocompromised infants aged six and four months with invasive gastrointestinal aspergillosis. Both patients presented with weight loss and diarrhea. The underlying disorders were combined immunodeficiency and transient hypogammaglobulinemia of infancy. The diagnosis of gastrointestinal aspergillosis was established by gastrointestinal endoscopy and histopathological examination of the tissue specimens. Both children responded well to Amphotericin B.