Colorectal cancers--experience at a regional cancer centre in India.
Article
Dans Anglais
| IMSEAR
| ID: sea-124297
ABSTRACT
BACKGROUND:
The incidence of colorectal cancer (CRC) shows a wide geographic variation and India along with other Asian and African countries has a low incidence. Most patients present with advanced disease and no uniform treatment guidelines are followed at present. PATIENTS ANDMETHODS:
An audit of 91 patients treated as per IRCH protocol between June 1994 and Jun 2000 in a single surgical unit was performed.RESULTS:
The mean age of patients was 45.3 years (18-90 years) and there was a predominance of rectal cancer patients (Rectal vs Colon = 76% vs 24%). Majority of the rectal cancers were low rectal cancers (67%) and abdominoperineal resection was the commonest surgical procedure performed(40). The inoperability rate was 24% and sphincter salvage rate was 13%. Seventy nine percent of patients had adenocarcinoma and 90% of CRC patients belonged to Astler-Collers stage B2 and C. A total of 37 patients also received adjuvant radiotherapy and only 39 out of 60 patients planned for adjuvant chemotherapy could complete the treatment. The operative mortality was 2.2% and morbidity was 18%. A total of 13 (14%) patients had relapse of disease (local 5, regional 3, distant 5).CONCLUSIONS:
A significant number of CRC patients in India present with advanced stage of disease and probably due to referral bias majority had low rectal cancers. By advocating multimodality protocols a good locoregional and systemic control can be achieved despite the advanced stage of presentation.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sujet âgé de 80 ans ou plus
/
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Tumeurs colorectales
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Analyse de survie
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Incidence
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Études rétrospectives
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Facteurs de risque
Type d'étude:
Etude d'étiologie
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Guide de pratique
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Etude d'incidence
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Étude observationnelle
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Étude pronostique
/
Facteurs de risque
Limites du sujet:
Aged80
Pays comme sujet:
Asie
langue:
Anglais
Année:
2001
Type:
Article
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