Calcium and phosphate homeostasis among normal Myanmar people, patients with pathologic bone fractures and recurrent renal stones

ABSTRACT

The serum calcium, phosphaye, alkaline phosphatase and urinary exdretion of calcium and phosphate were measure to judge the homeostasis status among apparently healthy Myanmar, pathologic bone fractures and recurrent renal stones. The calcium and phosphorus homeostasis was found to be the same as in literature among apparently healthy Myanmar of various age groups ranging from 10-90 yr of both sexes. The values decreased with advancing age and a rise was found around menopause in females. The levels of serum and urinary calcium, phosphorus, and serum akaline phosphatase found in the pathologic bone fractures suggested that high risk due to low bone density and malformation of matrix plays a major role, instead of hyperparathyroidism, in causing the fractures. The cause of recurrent renal stones in the majority of the subjects with normocalcemia and normocalceuria were found to be due to low GFR.