The in vitro activity of OPC-17116, a new 5-methyl substituted quinolone against Burkholderia (Pseudomonas) pseudomallei

 Fifty clinical isolates of Burkholderia(Pseudomonal) pseudomallei were tested by broth microdilution technique for susceptibility to OPC-17116 , a new 5-methyl substituted quinolone. The minimul inhibitory concentration (MIC) range was 1-8 µg/ml. The MIC 50 and MIC 90 were 2.6 µg/ml and 0.4 µg/ml, respectively.