Chromosomal abnormalities associated with mental retardation in female subjects.
Indian J Hum Genet
;
2009 Jan; 15(1): 28-31
Article
Dans Anglais
| IMSEAR
| ID: sea-138867
ABSTRACT
Chromosomal abnormalities are thought to be the most common cause of mental retardation (MR). However, apart from a few selected types with typical aneuploidy, like Downs syndrome, Klinefelter syndrome, Turner syndrome, etc., the frequency of detectable chromosomal abnormalities in association with idiopathic MR is very low. In this study, we have investigated chromosomal abnormalities in female MR subjects (n = 150) by high-resolution GTG banding. Of them, 30 cases were diagnosed as Downs syndrome. Among the remaining (n = 120), chromosomal abnormalities/marked polymorphisms were detectable in only three MR cases (0.025).
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Polymorphisme génétique
/
Femelle
/
Humains
/
Aberrations des chromosomes
/
Zébrage chromosomique
/
Syndrome de Down
/
Caryotype
/
Déficience intellectuelle
langue:
Anglais
Texte intégral:
Indian J Hum Genet
Année:
2009
Type:
Article
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