Beijing genotype and other predominant Mycobacterium tuberculosis spoligotypes observed in Mashhad city, Iran.
Indian J Med Microbiol
;
2009 Oct-Dec; 27(4): 306-310
Article
Dans Anglais
| IMSEAR
| ID: sea-143597
ABSTRACT
Purpose:
The purpose of this study was to understand the molecular epidemiology of tuberculosis in Khorasan province of Iran was studied by spoligotyping 113 Mycobacterium tuberculosis isolates. The spoligotyping results were in comparison to the word Spoligotyping Database of Institute Pasteur de Guadeloupe (SpolDB4). Spoligotyping data from Iran has rarely been described and there is limited information on the major circulating clades of M. tuberculosis in Iran. Materials andMethods:
Spoligotyping was performed on 113 M. tuberculosis isolates from Mashhad patients between November 2004 and September 2005.Results:
The study found 57 spoligopatterns. 17 clusters and 32 true orphan genotype. The biggest cluster with 13 isolates had not been previously reported. The Beijing genotype was seen in eight (7.1%) isolates.Conclusions:
Genotyping and Spoligotyping gives a unifying framework for both epidemiology and evolutionary analysis of M. tuberculosis populations.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
langue:
Anglais
Texte intégral:
Indian J Med Microbiol
Thème du journal:
Microbiology
Année:
2009
Type:
Article
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