Your browser doesn't support javascript.
loading
Use of antimicrobial agents and granulocyte colony stimulating factors for febrile neutropenia in cancer patients in a tertiary care hospital in India.
Indian J Cancer ; 2010 Oct-Dec; 47(4): 430-436
Article Dans Anglais | IMSEAR | ID: sea-144384
ABSTRACT

Background:

Use of antimicrobials (AM) and granulocyte colony stimulating factors (G-CSF) affect the outcome and cost of treatment of febrile neutropenia (FN). There are no studies describing the AM utilization pattern or the use of G-CSF and cost incurred on them in cancer patients with FN from India. Materials and

Methods:

A study was conducted in a tertiary care, teaching hospital in New Delhi, India, with the objectives of describing the utilization pattern of AM and G-CSF in cancer patients with FN. The efficacy and costs of AM and G-CSF prescribed were also assessed.

Results:

A total of 211 patients with FN were enrolled in the study. A majority of 207 (98.1%) were in the low-risk category. The average number of AM used per patient was 2.45 ± 0.02 and the AM exposure density was 1.19. All patients were administered five different combinations of AM regimens and G-CSF, irrespective of the risk category. No difference in the time to defervesence or in the recovery of ANC counts were observed with the different AM regimens. The average drug cost per febrile neutropenia episode (FNE) was Rs 4694.45 ± 296.35 (113.95 ± 7.19$). G-CSF accounted for 76.14 - 97.58% of the total costs.

Conclusion:

Large variations in the pattern of AM prescribed with routine use of G-CSF, irrespective of the risk status, was observed. Guidelines for the rational and cost-effective use of AM and G-CSF in patients with FN needed to be prepared. This was especially important as treatment was given free of cost to all patients admitted in the government health facility.
Sujets)

Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Types de pratiques des médecins / Sujet âgé / Femelle / Humains / Mâle / Études de cohortes / Facteur de stimulation des colonies de granulocytes / Adolescent / Adulte / Jeune adulte Type d'étude: Etude d'étiologie / Guide de pratique / Etude d'incidence / Étude observationnelle / Étude pronostique / Facteurs de risque Pays comme sujet: Asie langue: Anglais Texte intégral: Indian J Cancer Année: 2010 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Types de pratiques des médecins / Sujet âgé / Femelle / Humains / Mâle / Études de cohortes / Facteur de stimulation des colonies de granulocytes / Adolescent / Adulte / Jeune adulte Type d'étude: Etude d'étiologie / Guide de pratique / Etude d'incidence / Étude observationnelle / Étude pronostique / Facteurs de risque Pays comme sujet: Asie langue: Anglais Texte intégral: Indian J Cancer Année: 2010 Type: Article