Alpha-adrenergic receptor blocking effect of Cleistanthus collinus (Roxb.) Benth. and Hook f. leaf extract on guinea pig isolated smooth muscle preparations.
Indian J Exp Biol
;
2011 May; 49(5): 339-342
Article
Dans Anglais
| IMSEAR
| ID: sea-145135
ABSTRACT
Aqueous extract of C. collinus leaves inhibited norepinephrine induced contraction in guinea pig vas deferens and aortic strip in a dose-dependent manner. Inhibition of acetylcholine induced contraction in ileum was dose independent. C. collinus extract per se had no effect on isolated guinea pig vas deferens and aortic strip, but inhibited norepinephrine induced contraction in a dose-dependent manner probably by its antagonist action on α-adrenergic receptor. It had inconsistent effect on guinea pig ileum in vitro preparation.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
2011
Type:
Article
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