Ovarian hemangioma with stromal luteinization and HCG-producing mononucleate and multinucleate cells of uncertain histogenesis: A rare co-existence with therapeutic dilemma.
Indian J Pathol Microbiol
;
2012 Oct-Dec 55(4): 509-512
Article
Dans Anglais
| IMSEAR
| ID: sea-145647
ABSTRACT
A 21 year old female presented with amenorrhea, hirsutism and change in voice along with an elevated serum β-HCG (human chorionic gonadotrophin) level and normal CA-125 level. Laparotomy revealed an enlarged right ovary measuring 6 × 5 × 1 cms with presence of an ovarian hemangioma along with stromal luteinization and HCG producing mononucleate as well as multinucleate cells of uncertain histogenesis on histopathological examination. Immunohistochemistry for inhibin and calretinin were positive in the luteinized component whereas β-HCG and Ki-67 were positive in the multinucleate cell component. The diagnostic rarity and therapeutic dilemma of such a rare mixed tumor within a single ovary has proven to be an exceptional case and an excellent investigative opportunity.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Tumeurs de l'ovaire
/
Femelle
/
Humains
/
Troubles de la voix
/
Cellules stromales
/
Antigènes CA-125
/
Lutéinisation
/
Jeune adulte
/
Aménorrhée
/
Gonadotrophine chorionique
langue:
Anglais
Texte intégral:
Indian J Pathol Microbiol
Année:
2012
Type:
Article
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